Recent Publications

Scientific Journal Cover

1. Ko, Y. P., Kang, M., Ganesh, V. K., Ravirajan, D., Li, B., and Hook, M. (2016) Coagulase and Efb of Staphylococcus aureus Have a Common Fibrinogen Binding Motif. MBio 7

2. Prasad, J. M., Gorkun, O. V., Raghu, H., Thornton, S., Mullins, E. S., Palumbo, J. S., Ko, Y. P., Hook, M., David, T., Coughlin, S. R., Degen, J. L., and Flick, M. J. (2015) Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense. Blood 126, 2047-2058

3. Neacsu, C. D., Ko, Y. P., Tagariello, A., Rokenes Karlsen, K., Neiss, W. F., Paulsson, M., and Wagener, R. (2014) Matrilin-1 is essential for zebrafish development by facilitating collagen II secretion. J. Biol. Chem. 289, 1505-1518

4. Ko, Y. P., Kuipers, A., Freitag, C. M., Jongerius, I., Medina, E., van Rooijen, W. J., Spaan, A. N., van Kessel, K. P., Hook, M., and Rooijakkers, S. H. (2013) Phagocytosis escape by a Staphylococcus aureus protein that connects complement and coagulation proteins at the bacterial surface. PLoS Pathog 9, e1003816

5. Kang, M., Ko, Y. P., Liang, X., Ross, C. L., Liu, Q., Murray, B. E., and Hook, M. (2013) Collagen-binding microbial surface components recognizing adhesive matrix molecule (MSCRAMM) of Gram-positive bacteria inhibit complement activation via the classical pathway. J. Biol. Chem. 288, 20520-20531* co-first authorship

6. Ko, Y. P., Liang, X., Smith, C. W., Degen, J. L., and Hook, M. (2011) Binding of Efb from Staphylococcus aureus to fibrinogen blocks neutrophil adherence. J. Biol. Chem. 286, 9865-9874

7. Ganesh, V. K., Rivera, J. J., Smeds, E., Ko, Y. P., Bowden, M. G., Wann, E. R., Gurusiddappa, S., Fitzgerald, J. R., and Hook, M. (2008) A structural model of the Staphylococcus aureus ClfA-fibrinogen interaction opens new avenues for the design of anti-staphylococcal therapeutics. PLoS Pathog 4, e1000226

8. Nicolae, C., Ko, Y. P., Miosge, N., Niehoff, A., Studer, D., Enggist, L., Hunziker, E. B., Paulsson, M., Wagener, R., and Aszodi, A. (2007) Abnormal collagen fibrils in cartilage of matrilin-1/matrilin-3-deficient mice. J. Biol. Chem. 282, 22163-22175

9. Wagener, R., Ehlen, H. W., Ko, Y. P., Kobbe, B., Mann, H. H., Sengle, G., and Paulsson, M. (2005) The matrilins--adaptor proteins in the extracellular matrix. FEBS Lett. 579, 3323-3329

10. Ko, Y. P., Kobbe, B., Paulsson, M., and Wagener, R. (2005) Zebrafish (Danio rerio) matrilins: shared and divergent characteristics with their mammalian counterparts. Biochem. J. 386, 367-379

11. Chang, Y. W., Chen, S. C., Cheng, E. C., Ko, Y. P., Lin, Y. C., Kao, Y. R., Tsay, Y. G., Yang, P. C., Wu, C. W., and Roffler, S. R. (2005) CD13 (aminopeptidase N) can associate with tumor-associated antigen L6 and enhance the motility of human lung cancer cells. Int. J. Cancer 116, 243-252

12. Wu, C. H., Balasubramanian, W. R., Ko, Y. P., Hsu, G., Chang, S. E., Prijovich, Z. M., Chen, K. C., and Roffler, S. R. (2004) A simple method for the production of recombinant proteins from mammalian cells. Biotechnol. Appl. Biochem. 40, 167-172

13. Ko, Y., Kobbe, B., Nicolae, C., Miosge, N., Paulsson, M., Wagener, R., and Aszodi, A. (2004) Matrilin-3 is dispensable for mouse skeletal growth and development. Mol. Cell. Biol. 24, 1691-1699

14. Kao, Y. R., Shih, J. Y., Wen, W. C., Ko, Y. P., Chen, B. M., Chan, Y. L., Chu, Y. W., Yang, P. C., Wu, C. W., and Roffler, S. R. (2003) Tumor-associated antigen L6 and the invasion of human lung cancer cells. Clin. Cancer Res. 9, 2807-2816