Antibody fragments, in particular the scFvs, Fabs, and VHH/VH retain full antigen-binding capacity and superior properties for research, diagnostic, and therapeutic applications. We offer the guaranteed antibody fragment services that provide high-quality soluble antibody fragments at very competitive prices and timelines. Customers simply provide us with the protein sequence of the antibody fragment and we will take care of the whole process from gene synthesis to final purified antibody fragment.

Guaranteed antibody fragment services with unprecedented assurances

  • Gene synthesis and sub cloning are included in the package – no additional cost to you.
  • Guarantee the solubility, purity and amount of antibody fragment – no cost to you if we can not meet these order specifications.
  • We never refold fragments from inclusion bodies.
  • Competitive price - starting from $2,500.
  • Fast turnaround time - as soon as 7 weeks.

 

                                                        Package Outlines

Fragment

Expression System

Amount

Purity

Timeline

Price

VHH/VH

E. coli

≥10 mg

≥90%

7 weeks

$2,500

scFV

E. coli

≥10 mg

≥90%

7 weeks

$3,000

Fab

E. coli

≥5 mg

≥90%

8 weeks

$3,500

  • Terms and Conditions:Only those eligible scFv/VHH/Fab sequences determined by our scientists during pre-project analysis will qualify for the guaranteed services.
  • To increase the expression level of your antibody fragment, codon optimization may be performed during fragment gene synthesis.
  • We never refold the expressed antibody fragments.
  • There may be a few (<3) amino acid residues left over in the desired construct, which are usually glycine and serine residues and will not affect protein functionality.
  • Customers can obtain their synthetic fragment gene in pET- or pCold-based vector for an additional price of $350 (please specify this during quotation inquiry).
  • Format of QA/QC: SDS-PAGE to determine the purity, and BCA™ Protein Assay or A280nm to measure the protein concentration.