A world-class structural biology resource that supports multi-investigator, multi-institutional research and accelerate drug discovery and therapeutic development using advanced ion mobility mass spectrometry (IMS) technology. The CAMP will primarily focus on studying the structure and function of membrane proteins, including their interactions with lipid and/or drug molecules, using IMS technology.

Major Equipment
• Synapt HDMS System - Capable of high efficiency ion mobility separations (IMS). Differentiate samples based on size, shape, and charge, as well as mass. Improved analytical benefits such as conformational analysis, the ability to separate different compound classes, remove background and interferences,
or carry out comprehensive structural characterization.
• mosquito LCP - automated membrane protein crystallisation screening, optimisation and scale-up.
• dragonfly screen optimiser - enables complex assay gradients or optimisation screens to be rapidly and accurately prepared, even with viscous liquids, while eliminating cross-contamination.

Core Leadership

Dr. Art Laganowsky
Arthur Laganowsky
Assistant Professor
Core Director
Center for Infectious and Inflammatory Diseases
713.677.7541
alaganowsky@ibt.tamhsc.edu